I can't get it to work in compatibility mode or anything on 7 64-bit. The community modified version works fine in 7, though.
Of course it works great on PPC Mac through classic mode on OSX 10.4.
BoE & the trilogy work fine using Wine on Linux.
I haven't tried BoE or the trilogy on an Intel Mac, because seriously, if I want a PC that doesn't do much in the way of useful things, I'll just build one & put Linux on it. Besides, without Classic support(which was abandoned as I recall), it wouldn't work anyway(though I hear there's a program to bring it back, but eh).