This is an interesting idea.
Ages ago I tried to convert some of the Exile creatures and character types into the GURPS system.
Regarding Geneforge, though, I think that the best sort of pen & paper system to use would be Amber diceless-- namely because with that you can easily incorporate the effect of the canisters. Your typical character will start with maybe 25 points, and each canister could increase this total by five. But the net sum would lead to a sanity rating.
I'd post a link to an explanation of the Amber Diceless system, but can't seem to find a good one.
Best of luck, though!
