there were already a couple cities that didn't play a major role in avernum/exile 2, so i guess the answer is maybe. some possible answers:no major role, because the empire invaded it and it's a major base that we can't enter. major role because it's a major base we can enter. major role because kyass is putting his problems with avernum aside for the time being, or at least sees the empire as just as much of an enemy. major role, but only because the empire took it over and decided to change its name to harston.
i want to say this is impossible, but 4 had an ending where you didn't have to kill rentar, so i guess anything is possible, after all. i can't think of anything really better than the canon ending, though. maybe some bad endings if you pick the wrong guilty party.
as for myself, i'd like to see a return of hostile1 and hostile2. it's not something that'd be used often at all, but seeing archers from 2 cities at war with each other (i think spire and bargha in 4, but my memory might be off) seeing each other...and then shooting only at me..just kind of bothered me. i might just ragequit if the zombies and empire soldiers in that one fort in avernum 2 don't fight each other just as much as they fight me. other than that, more new magic items.